Experimental determination of the energy response of alanine pellets in the high dose rate 192Ir spectrum.

نویسندگان

  • B Schaeken
  • R Cuypers
  • J Goossens
  • D Van den Weyngaert
  • D Verellen
چکیده

An experimental determination of the energy correction factor for alanine/paraffin pellets in the 192Ir spectrum at varying distances from the source is presented. Alanine dosimeters were irradiated in water under full scatter conditions with a high dose rate (HDR) 192Ir source (Flexisource), using a dedicated holder. Up to six line sources (catheters) fit in a regular pattern at fixed radial distances from the holder axis, the alanine detector being placed at the centre of the holder. The HDR source was stepping every 0.5 cm within a trocar needle within ± 3.0 cm around the medial plane through the detector in order to achieve dose homogeneity within the detector volume. The energy correction factor of alanine/paraffin pellets in 192Ir relative to 60Co was experimentally determined as the inverse ratio of the dose to water measured in water around the 192Ir source to the dose to water calculated in water using the TG-43 formalism. The pellets were read out with a Bruker EMX(micro) spectrometer (X-band). The amplitude of the central line in the alanine absorption spectrum from pellets irradiated within the 192Ir spectrum was directly compared with the amplitude from 60Co-irradiated pellets. The energy correction factors of Harwell pellets irradiated in the 192Ir spectrum are 1.029 ± 0.02, 1.027 ± 0.02 and 1.045 ± 0.02 at a mean weighted source–detector distance of 2.0, 2.9 and 5.3 cm, respectively. The experimentally obtained values for the energy response are 1.3% lower compared to the theoretical values for radial distances smaller than 3 cm.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Monte Carlo and experimental relative dose determination for an Iridium-192 source in water phantom

Background: Monte Carlo and experimental relative dose determination in a water phantom, due to a high dose rate (HDR) 192Ir source is presented for real energy spectrum and monochromatic at 356 keV. Materials and Methods: The dose distribution has been calculated around the 192Ir located in the center of 30 cm ×30 cm ×30 cm water phantom using MCNP4C code by Monte Carlo method. Relati...

متن کامل

Calibration of iridium-192 source by ionization chamber for high dose rate brachytherapy

Background: The effectiveness and safety of brachytherapy treatment is mainly concerned with the calibration of sources and their traceability to internationally accepted Standards. Secondary Standard Dosimetry Laboratory (SSDL) does not offer calibration of ionization chambers with gamma-ray spectrum of high dose rate source 192Ir . This work has been carried out to calibrate the high dose rat...

متن کامل

Determination of Dosimetric characteristics of a New 192Ir-PDR Brachytherapy Source According to AAPM TG- 43 Protocol using Monte Carlo simulation technique

Introduction: 192Ir is one of the important sources frequently used in brachytherapy. Up to now, a lot of commercial models of this source have been made which Ir-192 has been recently added to them. The aim of the present study is to determine the dosimetric parameters of this new source model based on the recommendations of TG-43(U1) protocol using Monte Carlo simulation tech...

متن کامل

Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources

Objective: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determination of dosimetric parameters for brachytherapy sources. The aim of this study is to obtain TG-43 dosimetric parameters for 60Co, 137Cs, 192Ir and 103Pd brachyt...

متن کامل

The study of dose gamma rays of 192Ir source on DNA single strand break (SSB) and DNA double strand break (DSB) in soft tissue phantom

Introduction: Passage of ionizing radiation through the organs of living creatures develops clusters of damaged nucleotides inside the DNA rounds. 192Ir Gamma source is one of the most widely used sources in brachytherapy of cervical and prostate cancer. Thus, in this research, we investigated the flux of photons and its resulting secondary electrons, the single-strand break (S...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Physics in medicine and biology

دوره 56 20  شماره 

صفحات  -

تاریخ انتشار 2011